Drop Acid

by David Perlmutter
with Kristin Loberg

Be prepared when you read Drop Acid for a book that concentrates on a medical theory that attributes many of our medical woes including obesity, diabetes, nonalcoholic fatty liver disease, premature death, stroke, coronary artery disease, Alzheimer’s and hypertension to high levels of uric acid. In his efforts to convince the reader of his theory, Dr. Perlmutter, a neurologist, spends about half of his book expounding in detail the scientific basis of the principles of his LUV (Lower Uric Values) Diet, a trademarked designator. He spends a further 16% of the book at the end on notes for further reading.

The second part of Drop Acid lays out a plan of action for the reader to follow in lowering uric acid levels in three main areas: food; sleep, exercise, exposure to nature, and timing of meals; followed by fine tuning the process. He concludes with recipes that he developed with Tricia Williams, a food therapist.

I was really excited to read this potentially life-changing book. Unfortunately, my eyes glazed over during the details of the first half, and I failed to be convinced that this is a program I personally want to commit to. Even the recipes are challenging. Although Perlmutter claims substitutes can be made in ingredients, I have to ask why one would suggest recipes that specifically include Castelvetrano olives, za’atar seasoning, Tuscan kale, or dulse flakes.

I apply a healthy dose of skepticism when members of the medical community make a business out of healthcare. Perlmutter, in an effort at full disclosure, shares that he is on the board of directors of a company marketing a device, a continuous glucose monitor (CGM) to measure and monitor blood glucose, a device he maintains is not necessary for his program but would be very useful. He frequently in the text refers the reader both to that device and to his self-promoting website. He also introduces the website of Tricia Williams where his business is again promoted and ready-to-eat meals following this diet are available for purchase.

I am not a scientist or a medical professional, and I have not tried his program myself. I am reviewing the book for readability and appeal, not evaluating the efficacy of the LUV diet.

I would like to extend my thanks to NetGalley and to Little, Brown & Co. for giving me the opportunity to read this book in exchange for an honest review.

Rating: 2/5

Category: Health, Mind, and Body

Notes: 1. Perlmutter is the author of a family of five books focused on gluten-free diets. His flagship book for that effort is Grain Brain.
2. Perlmutter ties his Covid wagon to a uric acid star, seemingly willing to accept most of the pandemic deaths as the inevitable result of comorbidities associated with high uric acid rather than admit most could have been avoided with the right therapeutics.

Publication: February 15, 2022—Little, Brown, & Co.

Memorable Lines:

As you will soon learn, long before any symptoms develop, asymptomatic hyperuricemia may well be fomenting an unending, irreversible storm and subtly stoking biological processes that ultimately result in elevated blood sugar and blood pressure, bad cholesterol, excess body fat, and systemic inflammation, which opens the door for any number of chronic degenerative conditions.

Contrary to what Big Corn will tell you, fructose and glucose are not siblings with equal biological effects. Fructose is more like glucose’s evil twin: when you eat glucose, your body uses it to produce energy; but when you eat fructose, it triggers changes in the body that favor the storage of energy in the form of fat.

If elevated uric acid precedes and predicts biological mayhem and future risk for most chronic diseases, then we must start paying attention to this important metabolite.